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For example, it has been studied as an adjunctive treatment in certain neurological conditions (such as schizophrenia) owing to its activity in the central nervous system

Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity

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Hains G, Descarreaux M, Hains F

however, there are scenarios where inhibiting SIRT3 might be beneficial 181

In this context, some of the new formulations of adalimumab have removed or substantially lowered the concentration of the citrate buffer to a residual concentration of 1.2 mM [43, 44], which should minimize or prevent pain potentially associated with this buffer